Opportunities

Our Company is a platform for people who:
  • thrive in a collaborative environment;
  • have a courageous and curious nature;
  • uphold a high standard of integrity;
  • are passionately committed to their work.
We are proud to provide great salaries, opportunities for flexible working, training opportunities, flexible holidays, and healthcare support. Our team is a social group, with regular activities spanning everything from punting to pub visits. Can’t find an open position? If you think your principles are aligned with ours, we want to hear from you. Send us your CV and cover letter at careers@theolytics.com, and we'll be in touch.
Team Lead Cancer Biology Advert

Team Lead, Cancer Biology / Translational Development / Oncolytic Viruses
Team Lead, Cancer Biology / Translational Development / Oncolytic Viruses

We are looking for a Team Leader in Translational Development to join our growing multidisciplinary and dynamic team. This position represents an excellent opportunity for someone looking to take leadership responsibility in the development of an early stage oncolytic virus product through to clinical application. Applicants should have extensive laboratory research experience and a desire to continue in a laboratory-focused role whilst exhibiting strong team leadership.

The successful applicant will be working in a fast paced environment to manage a team of 3-5 scientists, design and execute experiments at the interface of cancer and virology and to deliver strategic research and development goals. The candidate must be able to prioritise and manage multiple research activities and possess a broad range of technical expertise and knowledge in virology, cancer biology, assay development  and/or immunology. We are looking for someone who is a self-starter, has excellent communication skills, can interact with a diverse group of scientific disciplines and is happy to jump in when required in what will be an exciting work environment.

Activities

  • Prioritisation of workloads and coordination of scientific work streams and processes.
  • Management and training of scientists and lab technicians.
  • Design and execution of research and development projects.
  • Develop novel assays for platform development and therapeutic evaluation.
  • Human tumour explant assays to generate efficacy and mechanism of action data to support regulatory applications.
  • Review and ensure the quality of scientific data to meet regulatory expectations.
  • Collation and presentation of research findings at both internal and external meetings.
  • Contribution to a range of key strategic documents including: reports and presentations, patent applications, and regulatory filings.

Required skills and experience

  • A PhD in Cancer Biology, Virology, Immunology or similar discipline, with at least 3-5 years postdoctoral research or industry experience.
  • A track record in managing projects and supervising junior employees.
  • Experience of primary human tumour handling, processing and characterisation of cell types by flow cytometry.
  • Knowledge of cancer biology.
  • Evidence of impactful research experience as demonstrated by high-quality publications, patents and/or presentations at national/international conferences.
  • Experience in drug development and translating a therapeutic candidate to the clinic.
  • Knowledge of health and safety regulations in a laboratory environment.
  • Strong written and verbal communication and presentation skills.
  • Strong IT skills (including proficiency with Word, Excel and PowerPoint), and comfort using shared drives.

Desirable skills, experience and attributes

  • Experience with regulatory applications and IND/CTA submission.
  • Experience working on haematological cancers, particularly multiple myeloma.
  • Experience working with oncolytic viruses and adenoviruses.
  • Pharmaceutical and/or biotech industry experience.
  • High motivation for, and commitment to, research on anticancer therapies and drug discovery.
  • Initiative, and a willingness and propensity to take on responsibility.
  • The ability to lead and energise others.
  • Experience applying for ethical consent from regulatory bodies.
  • Experience with toxicology/pharmacokinetics studies/in vivo mouse models.
  • A collaborative attitude with a flair for problem-solving.
Company Benefits: Salary of £45,000 - £55,000, excellent holiday allowance, flexible working hours, frequent company away days and socials, ongoing training and workshops and an employer-matched pension scheme.
Bioinformatician Advert

Bioinformatician
Bioinformatician

We are looking for a Bioinformatician to join our growing multidisciplinary and dynamic team. This position represents an excellent opportunity for someone looking to contribute to the development of methods to assess diversity amongst virus metagenomes. The successful applicant will be working in a fast-paced environment, designing and building bioinformatics tools and pipelines, and contributing to key strategic documents. The candidate must be a proactive, organised individual and possess a range of technical expertise across multiple platforms. We are looking for someone who is a self-starter, has excellent communication skills, can interact with a diverse group of scientific disciplines and is happy to jump in when required in what will be an exciting work environment.

Activities:

  • Designing and building bioinformatics tools and pipelines to process genomic datasets.
  • Developing methods for assessing diversity amongst virus metagenomes.
  • Working closely with wet lab scientists to guide NGS experiment design.
  • Cultivating collaborations with external (e.g. machine learning) specialists.
  • Contributing to key strategic documents, including reports, presentations and patent applications.

Essential skills and experience:

  • A proficiency in Python programming.
  •  Confident with VCS workflows, such as Git.
  • Some experience with other task-appropriate programming languages, including R, JavaScript and C.
  • Experience with bioinformatics software, including minimap2, bowtie2, FastQC, fastp, samtools, bcftools, CLC Genomics Workbench and IGV.
  • Comfortable working in and maintaining a UNIX-like (e.g. Linux, MacOS terminal) environment.
  • Ability to build FOSS from source and indpendently resolve dependency and compatibility issues.
  • Proven track record of extracting actionable insights from NGS datasets.
  • The ability to communicate effectively within a multi-disciplinary environment to drive decision making in NGS projects.

Desirable skills and experience:

  • Familiarity with long-read NGS - such as ONT MinION - its applications and data analyses.
  • Experience in haplotype phasing and/or variant calling.
  • Some understanding of cancer biology and/or virology.
  • Some experience in R&D project management.
  • Some experience mentoring & advising junior staff.
Open Application Advert

Open Application

If you think your principles are aligned with ours, we want to hear from you!