Team Lead, Cancer Biology / Translational Development / Oncolytic Viruses
We are looking for a Team Leader in Translational Development to join our growing multidisciplinary and dynamic team. This position represents an excellent opportunity for someone looking to take leadership responsibility in the development of an early stage oncolytic virus product through to clinical application. Applicants should have extensive laboratory research experience and a desire to continue in a laboratory-focused role whilst exhibiting strong team leadership.
The successful applicant will be working in a fast paced environment to manage a team of 3-5 scientists, design and execute experiments at the interface of cancer and virology and to deliver strategic research and development goals. The candidate must be able to prioritise and manage multiple research activities and possess a broad range of technical expertise and knowledge in virology, cancer biology, assay development and/or immunology. We are looking for someone who is a self-starter, has excellent communication skills, can interact with a diverse group of scientific disciplines and is happy to jump in when required in what will be an exciting work environment.
- Prioritisation of workloads and coordination of scientific work streams and processes.
- Management and training of scientists and lab technicians.
- Design and execution of research and development projects.
- Develop novel assays for platform development and therapeutic evaluation.
- Human tumour explant assays to generate efficacy and mechanism of action data to support regulatory applications.
- Review and ensure the quality of scientific data to meet regulatory expectations.
- Collation and presentation of research findings at both internal and external meetings.
- Contribution to a range of key strategic documents including: reports and presentations, patent applications, and regulatory filings.
Required skills and experience
- A PhD in Cancer Biology, Virology, Immunology or similar discipline, with at least 3-5 years postdoctoral research or industry experience.
- A track record in managing projects and supervising junior employees.
- Experience of primary human tumour handling, processing and characterisation of cell types by flow cytometry.
- Knowledge of cancer biology.
- Evidence of impactful research experience as demonstrated by high-quality publications, patents and/or presentations at national/international conferences.
- Experience in drug development and translating a therapeutic candidate to the clinic.
- Knowledge of health and safety regulations in a laboratory environment.
- Strong written and verbal communication and presentation skills.
- Strong IT skills (including proficiency with Word, Excel and PowerPoint), and comfort using shared drives.
Desirable skills, experience and attributes
- Experience with regulatory applications and IND/CTA submission.
- Experience working on haematological cancers, particularly multiple myeloma.
- Experience working with oncolytic viruses and adenoviruses.
- Pharmaceutical and/or biotech industry experience.
- High motivation for, and commitment to, research on anticancer therapies and drug discovery.
- Initiative, and a willingness and propensity to take on responsibility.
- The ability to lead and energise others.
- Experience applying for ethical consent from regulatory bodies.
- Experience with toxicology/pharmacokinetics studies/in vivo mouse models.
- A collaborative attitude with a flair for problem-solving.