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In vivo Pharmacologist;
Technician / Scientist

Everyone should have access to innovative therapies that represent the promise of lasting cures. At Theolytics we are working to transform patients’ lives, through world leading science, with a great team. Our discovery platforms harness the power of viruses to systematically identify therapies optimised for a chosen patient population, with a focus on oncology.

We are a supportive team that are passionate about working together to meet our collective goals. We enjoy spending time together – both in and out of work. Our values center around creating an environment that helps people to thrive (both personally and professionally), and we work hard to enable that for each member of the team.  

We are looking for an In Vivo Pharmacologist (Technician / Scientist level), familiar with pharmacokinetics, biodistribution and tumour models, to join our growing multidisciplinary team. This position represents an excellent opportunity for someone looking to take a key role in the discovery and development of an early stage oncolytic virus product through to clinical application. The successful applicant will be working in a fast paced environment with a team of scientists to design and execute experiments and to deliver strategic research and development goals.

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Activities

  • Design and execution of cutting edge research projects; 

  • Design, manage, and perform in vivo pharmacology studies to support candidate development;

  • Prioritisation of workloads and coordination of scientific work streams and processes;

  • Collation and presentation of research findings at internal meetings;

  • Contribution to a range of key strategic documents including: reports and presentations, patent applications, and regulatory filings.

Candidate Profile

Essential

  • BSc / Msc / PhD degree in a relevant scientific discipline with strong experience in cancer biology;

  • A significant level of hands on experience in performing in vivo experiments in oncology models for drug discovery and ability to work independently;

  • Experience performing i.t. / i.v / i.p administrations and establishing tumour models;

  • Familiarity with animal ethics regulations, experience with home office returns;

  • Wet lab experience, including cell culture experience;

  • Ability to work in an organised and methodical fashion, and keep excellent records;

  • Builds networks with other teams and external specialists in area;

  • Strong team player who enjoys working in a highly collaborative environment, and is adaptable to evolving business needs; 

  • Evidence of impactful research experience through publications, patents and/or presentations at national/international conferences

  • Strong IT skills (including proficiency with Word, Excel, OneNote and PowerPoint), and comfort using shared drives. 

 

Desirable 

 

  • Experience of in vivo imaging (e.g. bioluminescence);

  • Experience of IHC / IF / flow cytometry;

  • Experience of tissue dissociation, DNA extraction, QPCR;

  • Experience in handling and processing primary tissue samples;

  • Experience establishing stable cell lines;

  • Knowledge of cancer biology and the tumour microenvironment; 

  • Experience working with oncolytic viruses and/or adenoviruses;

  • High motivation for, and commitment to, research on anticancer therapies and drug discovery;

  • Initiative, and a willingness and propensity to take on responsibility;

  • A collaborative attitude with a flair for problem-solving.

 

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