Leadership, Board and Advisors


Charlotte Casebourne
CEO and Co-Founder

Charlotte believes in equitable access to effective therapies. In addition to her role with Theolytics, she is a Board Member of the UK BioIndustry Association. Previously with New Medicine Partners, Charlotte is an entrepreneur with international leadership, operational and management experience. She has worked with government ministries, national funding bodies and research institutes to transform life science technologies into commercially viable products. She previously held leadership roles with the WEF Global Shapers Network; HealthTech Women; and Hello Tomorrow. Charlotte graduated as a University of Cambridge Bioscience Enterprise M.Phil Scholar and was a shortlisted finalist for Cambridge Entrepreneur of the Year.

Margaret Duffy
CSO and Co-Founder

Margaret is committed to the translation of innovative biological approaches into viable patient care. With over ten years’ international research experience, she specialises in virology and leads the scientific teams in the discovery of powerful new oncolytic viruses for clinical development. Previously a Fellow with the Kay Kendall Leukaemia Fund at the University of Oxford, Margaret also spent several years as a Postdoctoral Researcher with the University of Glasgow and with Batavia Biosciences in Leiden as part of the Marie Curie Industry-Academia Partnerships programme. Margaret has a PhD in Adenoviral Gene Therapy from the University of Glasgow.

Kerry Fisher
Head of Therapeutic Development and Co-Founder

Kerry is dedicated to exploring how best to deliver therapeutic viruses, genes and proteins into the tumour microenvironment. As well as bridging the gap between our commercial and scientific strategies, he holds a lectureship with the University of Oxford. Previously with PsiOxus, Kerry has over 25 years’ experience in translating oncolytic viruses from new product innovation all the way through early clinical trials to commercial development. During his career, Kerry has filed more than a dozen patent applications and has authored over sixty peer-reviewed publications.  Kerry has a PhD in Therapeutic Gene Delivery from the University of Birmingham.

Ken Powell

Ken has over 35 years’ experience in the pharmaceutical and biotechnology sectors. He is an expert virologist and has been involved in the development of multiple drugs including antiviral compounds for Herpes, HIV, Hepatitis C and RSV. He is also the Chair of ReViral, a company developing antiviral drugs to treat Respiratory Syncytial Virus (RSV) infection. Previously Ken was the Executive Chairman of Q-Chip, a company developing novel formulations of drugs. He was also the Founder and CEO of Arrow Therapeutics, a specialised antiviral drug discovery company acquired by Astra-Zeneca in 2007. Ken has held a professorship with UCL and was a senior pharmaceutical executive with the Wellcome Foundation. He has a PhD in Virology from the University of Birmingham.

Andy McLean
Investor Director

Andy is the lead Life Sciences investor at Oxford Sciences Innovation (OSI), where he oversees a portfolio of 11 innovative life sciences companies. In this role, he was involved in seeding Evox Therapeutics, Vaccitech, and Lab282. Before joining OSI, Andy was a consultant in McKinsey & Company’s London office. He has a MBBS in Medicine and Surgery from the University of Western Australia and a BA (Hons) in Philosophy, Politics and Economics from the University of Oxford.

Richard Reschen
University Observer

Richard is a Senior Manager in the Biotech Licensing & Ventures group at Oxford University Innovation (OUI), where he specialises in evaluating, managing and out-licensing patented technology. Although his major specialism is in the Biotech and Pharmaceutical sectors, Richard also has experience in commercialising diverse types of technology and IP, such as copyrighted material. Prior to working at OUI, Richard worked as a Business Development Manager at the University of Cambridge and has spent time in the management consultancy and finance sectors. Richard has a PhD in Cancer Biology and an MPhil in Bioscience Enterprise from the University of Cambridge.

Len Seymour
SAB Chair and Co-Founder

Len is a Professor of Gene Therapies within the Department of Oncology at the University of Oxford. He was the Founding President of the British Society for Gene and Cell Therapy, is the Secretary and Trustee of the European Society of Gene and Cell Therapy and is an Executive Council Member of the International Society for Cell and Gene Therapy of Cancer. Len is also the Chair of the Scientific Advisory Board of the Chronic Granulomatous Disorder Research Trust, as well as the Chair of the Scientific Advisory Board of the Muscular Dystrophy Consortium.



Julie Farr
Head of Finance

Julie has over thirty years’ international finance experience across the US, Europe and Asia-Pacific, working with both private and listed companies. As Group Finance Controller for cancer diagnostics company VolitionRx, Julie worked with the C-Suite to up-list onto NYSE American and to raise multiple rounds of capital. She has worked with management teams within the biotech and technology sectors to raise both private financing and public capital, and has also led financial due diligence through M&A activities. Julie has a BA (hons) from the University of Cambridge in Management Studies with a Natural Sciences background. She qualified as a Chartered Accountant with BDO.

Carmen Bedford

Carmen recently completed her PhD in Virology at Cardiff University, which explored the role of RL13 in HCMV Pathogenesis. Previously, she studied for a BSc in Medical Genetics at Swansea University. During her time at Swansea, the Microbiology Society awarded her the Undergraduate Microbiology Prize for 2013. Upon graduation in 2014, she was awarded the Graduates’ Prize in Genetics. Carmen is focused on creating a future in which effective and safe therapies are available for all.

Nick Buxey
Junior Executive Assistant

Nicholas is passionate about creating highly effective organisations in which each individual can thrive. His expertise bridges people, operations and communications to support the Theolytics team to revolutionise patient care. Previously with Opus Energy, Nicholas has experience in areas including multi-channel marketing, event management and communications. He has also worked in various administrative support roles, and has been an active volunteer for heritage and wildlife charities. Nicholas holds a BA (Hons) in English and Italian Literature from the University of Warwick.

Claudia Carrieri
Team Lead, Platform Development

Claudia’s research interests fall at the intersection of genetics, genome editing, and transcriptomics, and how the application of advancements in these areas can revolutionise the drug discovery process. Claudia has over fifteen years’ experience in RNA biology, genome editing and cell-line Engineering. Previously a Senior Postdoctoral Fellow at the MRC Scottish Centre of Regenerative Medicine, she was also  the recipient of a European Molecular Biology Organisation Marie Curie Fellowship for an Interdisciplinary Postdoc between the EBI at Hinxton and the EMBL at Monterotondo. Claudia has a PhD in Functional Genomics from the International School for Advanced Studies, Trieste.

Bea Choi
Team Lead

Bea is committed to delivering the best therapies and care to patients. She has over fourteen years’ experience in Cellular Immunology and T-Cell Biology, and has worked in both commercial and academic roles. Previously a Senior Scientist with Immunocore, Bea has also worked as a Postdoctoral Researcher for academic organizations in the UK and USA where she focused on exploring and understanding HIV & HBV infection models in vitro. Bea holds a PhD in Immunology from Imperial College, London.

Matt Hayman
Lab Manager

Matthew enjoys supporting efficient, fun and successful teams to translate innovative research into effective cancer therapies. Formerly with Canterbury District Health Board in New Zealand, Matthew has over twenty years’ experience of researching diseases including brain cancer, immunodeficiency and rheumatoid arthritis. Matthew has worked in world-class medical laboratories in London, New Zealand and Australia, leading large teams on complex projects to deliver the best possible service for patients. Matthew has a PhD in Biochemistry from the University of Durham.

Egon Jacobus

Professionally, Egon focuses on understanding how best to exploit viruses for therapeutic use. Prior to Theolytics Egon was a Postdoctoral Researcher in the Oncology department at the University of Oxford, where he studied the interplay between oncolytic viruses and tumour hypoxia. He has accumulated over ten years’ expertise in the stem cell, gene and oncolytic virotherapy fields at educational institutions across Europe and the Americas. Egon has a PhD in Oncology from the University of Oxford.

Adam Marsden
Head of Bioinformatics

Adam is focused on finding and engineering software-based solutions to biological problems. Previously the Head of Bioinformatics at OXGENE (formerly Oxford Genetics), he developed automated high-throughput systems for lead discovery and optimisation. Adam has a decade of industry experience in next-generation sequencing, genomics and scientific software development behind him. Before OXGENE, Adam worked as a bioinformatician at Systems Biology Laboratory UK, where he developed computational methods to detect rare somatic recombination events in single-cell WGS datasets. Adam holds an MChem (Hons) in Physical and Theoretical Chemistry from the University of Oxford.

Deanna Saunders
Lab Technician

Deanna enjoys working in a research environment, honing her skills in tissue culture and maintenance of cell lines. Previously with Bio-Rad, Deanna has over two years’ manufacturing experience for antibody production. She has substantial knowledge of tissue culture, the control and diversification of virus stocks. She also understands and champions the importance of standardised processes within the drug discovery and clinical development processes.  Deanna has a BsC (Hons) in Biochemistry from the University of Worcester.

Eleanor Scott

Eleanor is a passionate cancer researcher with over five years’ experience in the field of oncolytic virotherapy. She recently completed her PhD in Oncology at the University of Oxford, for which she received a competitively-awarded Cancer Research UK Oxford Centre Prize Studentship. Previously, Eleanor studied for a BSc in Biochemistry at the University of Bristol, which included a Year Abroad spent at the German Cancer Research Centre (DKFZ) in Heidelberg, where she worked within the Tumour Virology division.

Kritika Sharad
Lab Technician

Kritika enjoys working at the forefront of innovation, technology and development. She believes in oncolytic viruses as a novel therapeutic approach for cancer patients. Previously with the Disability Resource Centre at the University of Cambridge, Kritika has more than eight years’ experience in the education sector. Before moving to the UK in 2014, she was a lecturer at Doon Para-Medical College in India, where she taught Cell Biology within the Biotechnology department. Kritika has an MSc in Biochemistry from HNB Garwhal University and an MPhil from the University of Solan.

William Taverner

William is passionate about the translation of science and innovation for the development of novel cancer therapies. Before joining Theolytics, William completed his PhD studies in Oncolytic Immunotherapy at the University of Oxford. He was a part of the synthetic biology doctoral training programme during his PhD studies, and his research interests focused on the application of synthetic biology approaches to the development of cancer killing viral agents. William also has a BSc and Mbiol in Genetics from the University of Leeds.

Suzanne Vjestica-Brown
People and Operations Manager

Previously the Head of Portfolio Services for Oxford Sciences Innovation (OSI), Suzanne has considerable experience supporting early stage companies to: secure funding; grow their teams; and scale-up facilities, in addition to successfully performing other commercial and operational activities. Suzanne has also spent over ten years working in law firms as both a legal executive and a paralegal, specialising in a range of areas across immigration, employment, commercial and corporate law. She is currently studying for her CIPD Level 7 in Human Resource Management.

Theo Litik
Head of Wellbeing

Since joining the company in January 2018, Theo has been promoted from Team Mascot to Head of Wellbeing. Always ready to win a staring contest, he keeps a watchful eye over the office. His extraordinary telepathic abilities and dry humour ensure that all conversations with him are guaranteed to be both private and highly amusing. As the company socialite, he’s always at the centre of any and all team-building activities, and has proven himself an excellent plus-one for both formal and informal gatherings.