Project Manager

Opportunity

Theolytics is seeking a highly organised and execution-focused Project Manager to coordinate the delivery and reporting of its Horizon Europe-funded OCTOPOD IV Phase 2a programme. This is a multi-partner international consortium project involving clinical sites in Spain and Canada.

The role will be central to ensuring compliant delivery of the programme, with a particular emphasis on the Dissemination and Communication Work Package, as well as overall project governance, reporting, and stakeholder coordination.

About us

Theolytics is a clinical-stage, oncology biotech with a mission to improve the lives of people impacted by cancer through the development of transformative oncolytic immunotherapies.

We have pioneered a new approach to develop best-in-class oncolytic immunotherapies suitable for direct and systemic intravenous delivery. The company is focused on the advancement of its lead programme THEO-260 in clinical trials with the ambition of providing better outcomes for patients with stroma-rich solid cancers, for whom current treatment options are limited.

THEO-260 is being investigated in two clinical trials for the treatment of women with Platinum-Resistant Ovarian Cancer (PROC), a Phase 1/2a trial called OCTOPOD-IV in the UK, Spain and Canada and OCTOPOD-IP in the US. Additional pipeline programmes in preclinical development include novel candidates developed for colorectal cancer and haematological malignancies, where there remains significant unmet need.

Theolytics was founded in 2017, is headquartered in Oxford UK, and is backed by international life sciences investors Taiho Ventures, M Ventures, Oxford Science Enterprises, Epidarex Capital, BGF, Sound Bioventures and Oxford University Innovation. Theolytics has also received competitive grant awards including from Horizon Europe and UK.

Theolytics is committed to creating, inspiring and protecting a culture of inclusivity and diversity in everything we do. We bring our authentic selves to work, and strive to find and support the best person for any given role within our team. Our recruitment leads with capability, values and performance.

Responsibilities

Horizon Europe Consortium Project Management

Act as the central coordination point across all consortium partners, including coordinating input from partners for technical and financial reporting
Maintain and track the overall project plan, milestones, deliverables, and critical path
Lead preparation and submission of all periodic and final reports in line with Horizon Europe requirements·
Ensure alignment between clinical, translational, and regulatory workstreams
Organise, chair and document consortium meetings· Manage risks, issues, and change control processes
Maintain audit-ready documentation and ensure compliance with EU grant rules
Liaise with the granting authority and respond to queries

Dissemination & Communication Work Package (Lead Responsibility)

Own and execute the Dissemination and Communication Plan
Coordinate external communications including conference presentations, and stakeholder engagement
Ensure compliance with Horizon Europe dissemination, open access, and visibility requirements
Manage project website, digital presence, and communication materials
Track and report dissemination KPIs (e.g. publications, reach, engagement)
Coordinate with partners to ensure timely and consistent messaging

Stakeholder & Partner Management

Build effective working relationships with clinical sites, academic partners, and vendors
Ensure clarity of roles, responsibilities, and deliverables across the consortium
Support resolution of cross-partner dependencies and bottlenecks
Facilitate communication across geographies and disciplines

Financial & Administrative Oversight

Support Theolytics’ finance team in tracking project budgets at a high level

Monitor partner spend vs. budget allocations

Support preparation of financial reports and cost justifications

Ensure alignment between technical progress and budget utilisation

Cross-Programme Coordination (Theolytics Pipeline Support)

Provide project management support, as required, across other Theolytics development programmes, including clinical and preclinical pipeline activities
Support coordination of investigator-sponsored or internally sponsored trials (e.g. IP-led studies), ensuring alignment with broader company timelines and priorities·
Assist in tracking key milestones, dependencies, and risks across programmes to support portfolio-level visibility
Facilitate information flow between programme teams, senior management, and external stakeholders
Contribute to establishing scalable project management processes and tools across the organisation

We’re looking for someone that has:

Proven experience managing complex, multi-stakeholder projects (ideally EU-funded programmes such as Horizon 2020 / Horizon Europe)
Experience in life sciences, biotech, or clinical research environments
Strong understanding of clinical trial processes and/or translational research workflows
Demonstrated experience in grant reporting and compliance
Experience coordinating international partners across academia and industry

It would be useful if you have:

Direct experience leading a Horizon Europe (or similar EU) dissemination work package
Familiarity with open science, publication strategies, and research communications
Experience working with CROs, clinical sites, or biomarker laboratories
Knowledge of oncology drug development Skills & Competencies
Exceptional organisational and programme management skills
High attention to detail, particularly in documentation and compliance
Strong written communication skills (grant reporting, scientific coordination)
Ability to operate across scientific, clinical, and administrative domains
Proactive, problem-solving mindset with strong ownership
Comfortable working in a fast-paced, resource-constrained SME environment

Key Deliverables / Success Metrics

On-time and compliant submission of all Horizon Europe reports
Successful delivery of project milestones and deliverables
High-quality execution of dissemination activities (publications, visibility, engagement)
Strong partner satisfaction and effective consortium collaboration
Audit readiness and zero material compliance issues

Company Benefits: Competitive salary and holiday allowance, flexible working hours, private medical insurance, company socials, ongoing training and workshops and an employer-matched pension scheme.

To apply: email PMrecruitment@theolytics.com with a CV and brief cover letter.

Please note, we are working with a recruitment partner, HLX Life Sciences on this recruitment who may contact you on our behalf as part of this process.

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